Septerna Inc is a clinical-stage biotechnology company pioneering a new era of G protein-coupled receptor (GPCR) oral small molecule drug discovery powered by a proprietary Native Complex Platform. Its industrial-scale platform aims to unlock the full potential of GPCR therapies. The group discovery and development of a pipeline of product candidates focused initially on treating patients in three therapeutic areas: endocrinology, immunology and inflammation, and metabolic disease. Its pipeline includes SEP-786 (PTH1R), SEP-631 (MRGPRX2), TSHR, GLP-1R, GIPR, and GCGR.
Quick Stats
Jan 30, 202646.3
AI Score
HOLD1.32
Volume Ratio
Next Earnings
14
+ve Days (30d)
16
-ve Days (30d)
SEPN Stock Summary
Last updated Jan 30, 2026
SEPN is currently trading at $23.34, positioned above its 200-day moving average of $16.7, indicating a long-term uptrend. The stock has a 52-week range of $4.17 to $30.5.
Technical Analysis: The 50-day moving average stands at $26.48, which is above the current price, indicating bearish near-term pressure. The RSI (Relative Strength Index) reads 37.195, suggesting the stock is neutral with balanced momentum.
Money Flow Indicators: The Chaikin Money Flow (20-day) is -0.402, which is negative, suggesting distribution or selling pressure. Our AI-powered investment score rates SEPN at 46.3/100 with a HOLD recommendation.
SEPN (Septerna, Inc. Common Stock) Indicators
Last updated Jan 30, 2026
| Indicator | Value |
|---|---|
| RSI(14) | 37.195 |
| CMF (20) | -0.402 |
| ROC (10) | -14.755 |
| ADX (14) | 20.554 |
| Indicator | Value |
|---|---|
| MACD (12,26,9) | -0.56 |
| AROONOSC (14) | -64.286 |
| WILLAMS %R (14) | -97.764 |
| MFI (14) | 32.68 |
SEPN Technical Chart
- Candlesticks: Green = price up, Red = price down. Body shows open/close, wicks show high/low.
- SMAs: Moving averages help identify trends. Price above SMA = bullish, below = bearish.
- Options OI: Shows max open interest strikes. High OI = significant price levels.
- Volume Profile: Shows price levels with most trading activity. POC = Point of Control (highest volume).
- Earnings: Vertical lines mark earnings dates. Watch for volatility around these dates.
- Gamma Walls: Key support/resistance from options gamma exposure. Orange = resistance above, Purple = support below.
- Fibonacci Retracement: Auto-calculated support/resistance levels based on recent high/low. Key levels: 23.6%, 38.2%, 50%, 61.8%, 78.6%.
- Unusual Activity: Highlights days with abnormal volume (2x+ average) or large price moves (5%+). Red marker = unusual activity detected.
Technical Indicators
Select indicators above to analyze technical patterns
Indicators will appear below the price chart with perfectly aligned datesVolume Profile Analysis
Horizontal histogram showing volume distribution at each price level with buying/selling pressure
SEPN Price vs Max Options Open Interest
SEPN Max Change In Options Open Interest
SEPN Options - Sort by Max open Interest (near term)
1st February 2026 (Data is delayed in normal mkt. hours)
| Type | Expiration | Strike | OI | Change in OI |
Volume | Ask | PC | Delta | Vega | Volatility | % change | Track |
|---|
SEPN Daily Out of Money Options - Sort by Max open Interest (near term)
1st February 2026 (Data is delayed in normal mkt. hours)
| Type | Expiration | Strike | OI | Change in OI |
Volume | Ask | PC | Delta | Vega | Volatility | % change | Track |
|---|
SEPN Daily In the Money Options - Sort by Max open Interest (near term)
1st February 2026 (Data is delayed in normal mkt. hours)
| Type | Expiration | Strike | OI | Change in OI |
Volume | Ask | PC | Delta | Vega | Volatility | % change | Track |
|---|
SEPN Most Active Options by Volume(near term)
1st February 2026 (Data is delayed in normal mkt. hours)
| Type | Expiration | Strike | Volume | OI | Change in OI |
Ask | PC | Delta | Vega | Volatility | % change | Track |
|---|
Septerna, Inc. Common Stock is not trading above both 50 Day and 200 Day SMA which is considered Bearish.
SEPN Moving Averages Analysis
Septerna, Inc. Common Stock has been above 200 day sma 1 times in last 30 days. Last time it was above 200 day sma was on Jan 30, 2026
SEPN (Septerna, Inc. Common Stock) Simple Moving Averages
Moving Averages are last updated Jan 30, 2026
| Days | MA |
|---|---|
| 10 | 25.41 |
| 20 | 25.86 |
| 30 | 26.68 |
| 50 | 26.48 |
| 100 | 22.98 |
| 200 | 16.7 |
SEPN Fundamental Analysis
| P/E (Forward) | 107.5269 |
| P/E (Trailing) | -- |
| Market Cap ($) | 1.0 billion |
| Earnings/Share ($) | -6.9 |
| Net Proft Margin (%) | -2.6677 |
| Dividend/Share ($) | -- |
| EPS Estimate Current Year ($) | -0.9374 |
| EPS Estimate Next Year ($) | -0.8387 |
| WallStreet Target Price ($) | 33.8571 |
| Most Recent Quarter |