Sionna Therapeutics Inc is a clinical-stage biopharmaceutical company on a mission to revolutionize the current treatment paradigm for cystic fibrosis (CF) patients by developing novel medicines that normalize the function of the cystic fibrosis transmembrane conductance regulator (CFTR) protein to deliver clinically meaningful benefit to CF patients. CF is a progressive and life-threatening genetic disease caused by inherited mutations in the CFTR gene, which heads to insufficient CFTR function. The Company is managed as one operating segment focused on the research and development of cystic fibrosis therapies.
Quick Stats
Jan 30, 202657.5
AI Score
HOLD0.96
Volume Ratio
Mar 19, 2026
Next Earnings
17
+ve Days (30d)
13
-ve Days (30d)
SION Stock Summary
Last updated Jan 30, 2026
SION is currently trading at $42.26, positioned above its 200-day moving average of $26.73, indicating a long-term uptrend. The stock has a 52-week range of $7.255 to $45.
Technical Analysis: The 50-day moving average stands at $41.37, which is below the current price, signaling bullish near-term momentum. The RSI (Relative Strength Index) reads 53.117, suggesting the stock is neutral with balanced momentum.
Money Flow Indicators: The Chaikin Money Flow (20-day) is 0.127, which is positive, indicating accumulation by institutional investors. Our AI-powered investment score rates SION at 57.5/100 with a HOLD recommendation.
SION (Sionna Therapeutics, Inc. Common Stock) Indicators
Last updated Jan 30, 2026
| Indicator | Value |
|---|---|
| RSI(14) | 53.117 |
| CMF (20) | 0.127 |
| ROC (10) | 8.777 |
| ADX (14) | 12.064 |
| Indicator | Value |
|---|---|
| MACD (12,26,9) | 0.488 |
| AROONOSC (14) | 71.429 |
| WILLAMS %R (14) | -20.178 |
| MFI (14) | 52.083 |
SION Technical Chart
- Candlesticks: Green = price up, Red = price down. Body shows open/close, wicks show high/low.
- SMAs: Moving averages help identify trends. Price above SMA = bullish, below = bearish.
- Options OI: Shows max open interest strikes. High OI = significant price levels.
- Volume Profile: Shows price levels with most trading activity. POC = Point of Control (highest volume).
- Earnings: Vertical lines mark earnings dates. Watch for volatility around these dates.
- Gamma Walls: Key support/resistance from options gamma exposure. Orange = resistance above, Purple = support below.
- Fibonacci Retracement: Auto-calculated support/resistance levels based on recent high/low. Key levels: 23.6%, 38.2%, 50%, 61.8%, 78.6%.
- Unusual Activity: Highlights days with abnormal volume (2x+ average) or large price moves (5%+). Red marker = unusual activity detected.
Technical Indicators
Select indicators above to analyze technical patterns
Indicators will appear below the price chart with perfectly aligned datesVolume Profile Analysis
Horizontal histogram showing volume distribution at each price level with buying/selling pressure
SION Price vs Max Options Open Interest
SION Max Change In Options Open Interest
SION Options - Sort by Max open Interest (near term)
2nd February 2026 (Data is delayed in normal mkt. hours)
| Type | Expiration | Strike | OI | Change in OI |
Volume | Ask | PC | Delta | Vega | Volatility | % change | Track |
|---|
SION Daily Out of Money Options - Sort by Max open Interest (near term)
2nd February 2026 (Data is delayed in normal mkt. hours)
| Type | Expiration | Strike | OI | Change in OI |
Volume | Ask | PC | Delta | Vega | Volatility | % change | Track |
|---|
SION Daily In the Money Options - Sort by Max open Interest (near term)
2nd February 2026 (Data is delayed in normal mkt. hours)
| Type | Expiration | Strike | OI | Change in OI |
Volume | Ask | PC | Delta | Vega | Volatility | % change | Track |
|---|
SION Most Active Options by Volume(near term)
2nd February 2026 (Data is delayed in normal mkt. hours)
| Type | Expiration | Strike | Volume | OI | Change in OI |
Ask | PC | Delta | Vega | Volatility | % change | Track |
|---|
Sionna Therapeutics, Inc. Common Stock is above both 50 Day and 200 Day SMA which is considered Bullish.
SION Moving Averages Analysis
Sionna Therapeutics, Inc. Common Stock has been above 50 day sma 1 times in last 30 days. Last time it was above 50 day sma was on Jan 30, 2026
Sionna Therapeutics, Inc. Common Stock has been above 200 day sma 1 times in last 30 days. Last time it was above 200 day sma was on Jan 30, 2026
SION (Sionna Therapeutics, Inc. Common Stock) Simple Moving Averages
Moving Averages are last updated Jan 30, 2026
| Days | MA |
|---|---|
| 10 | 41.7 |
| 20 | 40.33 |
| 30 | 41.24 |
| 50 | 41.37 |
| 100 | 36.4 |
| 200 | 26.73 |
SION Fundamental Analysis
| P/E (Forward) | 0 |
| P/E (Trailing) | -- |
| Market Cap ($) | 1.9 billion |
| Earnings/Share ($) | -1.8 |
| Net Proft Margin (%) | 0 |
| Dividend/Share ($) | -- |
| EPS Estimate Current Year ($) | -2.0314 |
| EPS Estimate Next Year ($) | -2.1371 |
| WallStreet Target Price ($) | 44.8571 |
| Most Recent Quarter |