Denali Therapeutics Inc is a biotechnology company that is engaged in developing and discovering therapeutics to defeat neurodegeneration disease. The company's development programs include the LRRK2 Inhibitor Program, which develops brain penetrant small molecule LRRK2 inhibitor product candidates for Parkinson's disease. Its key products include DNL201, DNL151, DNL747, ATV (Antibody Transport Vehicle), ETV (Enzyme Transport Vehicle), and others.
Quick Stats
Jan 30, 202659.7
AI Score
HOLD1.97
Volume Ratio
Feb 26, 2026
Next Earnings
18
+ve Days (30d)
12
-ve Days (30d)
DNLI Stock Summary
Last updated Jan 30, 2026
DNLI is currently trading at $21.74, positioned above its 200-day moving average of $15.62, indicating a long-term uptrend. The stock has a 52-week range of $10.57 to $24.345.
Technical Analysis: The 50-day moving average stands at $18.25, which is below the current price, signaling bullish near-term momentum. The RSI (Relative Strength Index) reads 68.922, suggesting the stock is neutral with balanced momentum.
Money Flow Indicators: The Chaikin Money Flow (20-day) is 0.227, which is positive, indicating accumulation by institutional investors. Our AI-powered investment score rates DNLI at 59.7/100 with a HOLD recommendation.
DNLI (Denali Therapeutics Inc. Common Stock) Indicators
Last updated Jan 30, 2026
| Indicator | Value |
|---|---|
| RSI(14) | 68.922 |
| CMF (20) | 0.227 |
| ROC (10) | 15.761 |
| ADX (14) | 28.688 |
| Indicator | Value |
|---|---|
| MACD (12,26,9) | 1.095 |
| AROONOSC (14) | 92.857 |
| WILLAMS %R (14) | -5.159 |
| MFI (14) | 83.529 |
DNLI Technical Chart
- Candlesticks: Green = price up, Red = price down. Body shows open/close, wicks show high/low.
- SMAs: Moving averages help identify trends. Price above SMA = bullish, below = bearish.
- Options OI: Shows max open interest strikes. High OI = significant price levels.
- Volume Profile: Shows price levels with most trading activity. POC = Point of Control (highest volume).
- Earnings: Vertical lines mark earnings dates. Watch for volatility around these dates.
- Gamma Walls: Key support/resistance from options gamma exposure. Orange = resistance above, Purple = support below.
- Fibonacci Retracement: Auto-calculated support/resistance levels based on recent high/low. Key levels: 23.6%, 38.2%, 50%, 61.8%, 78.6%.
- Unusual Activity: Highlights days with abnormal volume (2x+ average) or large price moves (5%+). Red marker = unusual activity detected.
Technical Indicators
Select indicators above to analyze technical patterns
Indicators will appear below the price chart with perfectly aligned datesVolume Profile Analysis
Horizontal histogram showing volume distribution at each price level with buying/selling pressure
DNLI Price vs Max Options Open Interest
DNLI Max Change In Options Open Interest
DNLI Options - Sort by Max open Interest (near term)
1st February 2026 (Data is delayed in normal mkt. hours)
| Type | Expiration | Strike | OI | Change in OI |
Volume | Ask | PC | Delta | Vega | Volatility | % change | Track |
|---|
DNLI Daily Out of Money Options - Sort by Max open Interest (near term)
1st February 2026 (Data is delayed in normal mkt. hours)
| Type | Expiration | Strike | OI | Change in OI |
Volume | Ask | PC | Delta | Vega | Volatility | % change | Track |
|---|
DNLI Daily In the Money Options - Sort by Max open Interest (near term)
1st February 2026 (Data is delayed in normal mkt. hours)
| Type | Expiration | Strike | OI | Change in OI |
Volume | Ask | PC | Delta | Vega | Volatility | % change | Track |
|---|
DNLI Most Active Options by Volume(near term)
1st February 2026 (Data is delayed in normal mkt. hours)
| Type | Expiration | Strike | Volume | OI | Change in OI |
Ask | PC | Delta | Vega | Volatility | % change | Track |
|---|
Denali Therapeutics Inc. Common Stock is above both 50 Day and 200 Day SMA which is considered Bullish.
DNLI Moving Averages Analysis
Denali Therapeutics Inc. Common Stock has been above 50 day sma 1 times in last 30 days. Last time it was above 50 day sma was on Jan 30, 2026
Denali Therapeutics Inc. Common Stock has been above 200 day sma 1 times in last 30 days. Last time it was above 200 day sma was on Jan 30, 2026
DNLI (Denali Therapeutics Inc. Common Stock) Simple Moving Averages
Moving Averages are last updated Jan 30, 2026
| Days | MA |
|---|---|
| 10 | 20.13 |
| 20 | 18.75 |
| 30 | 18.11 |
| 50 | 18.25 |
| 100 | 16.77 |
| 200 | 15.62 |
DNLI Fundamental Analysis
| P/E (Forward) | 0 |
| P/E (Trailing) | -- |
| Market Cap ($) | 3.4 billion |
| Earnings/Share ($) | -2.92 |
| Net Proft Margin (%) | 0 |
| Dividend/Share ($) | -- |
| EPS Estimate Current Year ($) | -3.0085 |
| EPS Estimate Next Year ($) | -2.9568 |
| WallStreet Target Price ($) | 32.8571 |
| Most Recent Quarter |