IONS Stock Analysis: Buy, Sell, or Hold?
IONS - Ionis Pharmaceuticals, Inc. Common Stock
$72.15
-2.09 (-2.82%)
▼
5d:
+1.63%
30d:
-10.48%
90d:
-10.41%
BUY
HIGH Confidence
Analysis Updated: Mar 27, 2026 12:00 AM ET
Earnings: Apr 29, 2026
29d
Smart Money Accumulation
IONS is down 3.7% this week, but smart money is accumulating calls. Top strike: $80 2026-05-15 with 23 OI. Call ratio: 67% View Scanner →
Strength: 3.6/10
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Interactive Price Chart (1 Month)
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Bottom Line:
✅ BUY SIGNAL: IONS shows strong fundamentals and good volume confirmation. Solid entry point despite slightly low pricing.
✅ BUY SIGNAL: IONS shows strong fundamentals and good volume confirmation. Solid entry point despite slightly low pricing.
In-depth Analysis How we analyze
Valuation Analysis: IONS is currently trading at $72.15, which is considered slightly low relative to its 30-day fair value range of $71.68 to $81.38.
Technical Outlook: Technically, IONS is in a strong uptrend. Immediate support is located at $68.90, while resistance sits at $75.63.
Market Sentiment: The stock shows a mixed technical setup (45/100), with neutral trendline and momentum signals. Wall Street analysts see significant upside, with an average price target of $96.81 (+34.2%). Combining these factors, the current setup offers a favorable risk/reward ratio for buyers.
Technical Outlook: Technically, IONS is in a strong uptrend. Immediate support is located at $68.90, while resistance sits at $75.63.
Market Sentiment: The stock shows a mixed technical setup (45/100), with neutral trendline and momentum signals. Wall Street analysts see significant upside, with an average price target of $96.81 (+34.2%). Combining these factors, the current setup offers a favorable risk/reward ratio for buyers.
Quick Decision Summary
Current Position
SLIGHTLY LOW
Fair Price Range
$71.68 -
$81.38
Company Quality Score
60/100
(BUY)
Volume Confirmation
HIGH
Confidence Score
82.6%
All Signals
- BULLISH: Price oversold vs 30-day range
- NEUTRAL: Mixed technical signals (45/100)
- BULLISH: High volume confirmation
- BULLISH: Trading 34.2% below Wall St target ($96.81)
Fair Price Analysis
30-Day Fair Range
$71.68 -
$81.38
Current vs Fair Value
SLIGHTLY LOW
Support & Resistance Levels
Support Level
$68.90
Resistance Level
$75.63
Current Trend
Strong Uptrend
Technical data as of
Mar 27, 2026
Fundamental Context
Forward P/E (Next Year Est.)
-115.98
Wall Street Target
$96.81
(+34.2%)
Revenue Growth (YoY)
-10.3%
Earnings Growth (YoY)
-43.7%
Profit Margin
-40.4%
Share & Embed Analysis
Last updated: March 30, 2026 7:02 AM ET
Data refreshes hourly during market hours. Next update: 8:02 AM
Data refreshes hourly during market hours. Next update: 8:02 AM
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Technical Signals Check
Is IONS showing a specific setup today?
Insider Activity (6 Months)
0
Buys
20
Sells
Net
INSIDERS SELLING
Recent Transactions
Elizabeth L Hougen
SELL
10172 shares
2026-03-17
Elizabeth L Hougen
SELL
215048 shares
2026-03-16
Brett P Monia
SELL
34103 shares
2026-03-10
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Advanced IONS Option Strategies
Professional options setups generated by AI based on today's IONS price and gamma walls.
