IONS Stock Analysis: Buy, Sell, or Hold?

IONS - Ionis Pharmaceuticals, Inc. Common Stock

PHARMACEUTICAL PREPARATIONS
$77.60
1.77 (2.33%) ▲
5d: +0.98%
30d: +1.09%
90d: -8.0%
BUY
HIGH Confidence
Analysis Updated: May 13, 2026 12:00 AM ET
Earnings: May 06, 2026 0d
Smart Money Distribution

IONS is up 4.5% this week, but smart money is buying puts. Top strike: $70 2026-06-18 with 303 OI. Put ratio: 100% View Scanner →

Strength: 7.2/10

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Interactive Price Chart (1 Month)

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💡
Bottom Line:
✅ BUY SIGNAL: IONS shows strong fundamentals and good volume confirmation. Solid entry point despite slightly high pricing.
See Forward Earnings Fair Value & Price Prediction →

In-depth Analysis How we analyze

Valuation Analysis: IONS is currently trading at $77.60, which is considered slightly high relative to its 30-day fair value range of $73.82 to $76.22.

Technical Outlook: Technically, IONS is in a strong uptrend. The price is approaching resistance at $77.76. A breakout above this level would be a bullish signal, while rejection here could lead to consolidation.

Market Sentiment: IONS has a strong technical setup (75/100), with favorable trendlines, momentum, and price action for short-term traders. Wall Street analysts see significant upside, with an average price target of $100.74 (+29.8%). Combining these factors, the current setup offers a favorable risk/reward ratio for buyers.

Quick Decision Summary

Current Position SLIGHTLY HIGH
Historical Trading Range $73.82 - $76.22
Company Quality Score 63/100 (BUY)
Volume Confirmation HIGH
Confidence Score 78.9%

All Signals

  • BULLISH: Strong technical setup (75/100)
  • BULLISH: High volume confirmation
  • BULLISH: Trading 29.8% below Wall St target ($100.74)

Trading Range Analysis

30-Day Trading Range $73.82 - $76.22
Current vs Trading Range SLIGHTLY HIGH

Support & Resistance Levels

Support Level $72.94
Resistance Level $77.76
Current Trend Strong Uptrend
Technical data as of May 13, 2026

Fundamental Context

Forward P/E (Next Year Est.) -125.18
Wall Street Target $100.74 (+29.8%)
Revenue Growth (YoY) 87.0%
Earnings Growth (YoY) -43.7%
Profit Margin -30.9%
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Last updated: May 14, 2026 10:41 AM ET
Data refreshes hourly during market hours. Next update: 11:41 AM
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Ticker Score Recommendation Change %
Insider Activity (6 Months)
0
Buys
20
Sells
Net
INSIDERS SELLING
Recent Transactions
Kyle Jenne SELL 4902 shares 2026-04-16
Brian Birchler SELL 973 shares 2026-04-16
B Lynne Parshall SELL 5000 shares 2026-04-15

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Advanced IONS Option Strategies

Professional options setups generated by AI based on today's IONS price and gamma walls.

Iron Condor Bull Call Bear Put Collar

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