KRYS Stock Analysis: Buy, Sell, or Hold?

KRYS - Krystal Biotech, Inc. Common Stock

BIOLOGICAL PRODUCTS, (NO DISGNOSTIC SUBSTANCES)
$304.23
2.18 (0.72%) ▲
5d: -3.82%
30d: +10.25%
90d: +16.21%
HOLD
MODERATE Confidence
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Analysis Updated: May 21, 2026 12:00 AM ET
Earnings: May 11, 2026 0d

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Interactive Price Chart (1 Month)

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💡
Bottom Line:
📊 HOLD: KRYS is fairly valued with market pricing in 2.8% annual growth. Fine to hold or accumulate slowly on dips.
See Forward Earnings Fair Value & Price Prediction →

Long-Term Wealth Forecast (2031)

Based on Analyst Consensus Growth & Historical Valuation

0% (Stagnation) 50% (Hyper Growth)
EST. PRICE IN 2031
$444.16
Based on 12.2% avg growth
INTRINSIC VALUE TODAY
$275.79
Trading above historical range

How this is calculated: We use a Growth Decay Model: starting with analyst consensus growth (adjusted above) and gradually slowing it down to a long-term terminal rate (4%) by Year 5. This provides a more realistic valuation than assuming constant hyper-growth. We then apply a 25.0x Exit PE.

In-depth Analysis How we analyze

Valuation Analysis: KRYS is currently trading at $304.23, which is considered extended relative to its 30-day fair value range of $266.98 to $302.17. The stock's valuation (Forward PE: 30.2) is in line with its historical norms (27.8). At these levels, the market is pricing in 2.8% annual earnings growth. This growth rate appears achievable given the company's track record, suggesting the valuation is rational.

Technical Outlook: Technically, KRYS is in a uptrend. Immediate support is located at $286.00, while resistance sits at $319.48.

Market Sentiment: The stock shows a mixed technical setup (55/100), with neutral trendline and momentum signals. In the options market, Implied Volatility is low (0th percentile), suggesting options premiums are relatively cheap. This makes it an attractive time for long options strategies if you have a directional bias. The stock is fairly positioned - fine to hold existing positions or accumulate slowly on dips, but not an urgent buy.

Quick Decision Summary

Current Position EXTENDED
Historical Trading Range $266.98 - $302.17
Company Quality Score 60/100 (BUY)
Volume Confirmation HIGH
Confidence Score 57.3%

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All Signals

  • BEARISH: Price extended above range
  • BULLISH: Options cheap (IV 0th percentile)
  • NEUTRAL: Mixed technical signals (55/100)
  • BULLISH: High volume confirmation
  • NEUTRAL: Near Wall St target ($322.78)
  • NEUTRAL: Market pricing in 2.8% annual earnings growth - fairly valued

Trading Range Analysis

30-Day Trading Range $266.98 - $302.17
Current vs Trading Range EXTENDED
Expected Move (7 Days) ±$16.30 (5.4%)

Support & Resistance Levels

Support Level $286.00
Resistance Level $319.48
Current Trend Uptrend
Technical data as of May 21, 2026

Fundamental Context

Forward P/E (Next Year Est.) 30.18
Wall Street Target $322.78 (+6.1%)
Revenue Growth (YoY) 31.9%
Earnings Growth (YoY) 52.5%
Profit Margin 53.9%
Valuation Premium vs History +2.8% premium
PE vs Historical 30.2 vs 27.8 FAIR
Market-Implied Price Targets If current PE multiple persists
Implied Growth (YoY): +2.8% (market-implied from PE analysis)
1-Year Target $312.75 (+3%)
2-Year Target $321.51 (+6%)
3-Year Target $330.51 (+9%)
3-Yr Target (if PE normalizes) (PE: 30→28) PE COMPRESSION $304.44 (+0%)
Earnings growth offset by PE compression
3-Year Scenarios Using analyst projected EPS growth
Bull: (PE: 30.2, Growth: 20.3%) $530.29 (+74%)
Base: (SPY PE: 22.0, Growth: 20.3%) $386.38 (+27%)
Bear: (PE: 18.7, Growth: 20.3%) $328.42 (+8%)
📈 Valuation based on Current Earnings
RECOVERY PLAY: Stock looks expensive now (40x PE), but valuation improves significantly next year (30x PE) as earnings recover.
Trailing PE: 40.26 | Current EPS (TTM): $7.46
Bull Case $446.40 (+47%)
Analyst growth 35.1%, PE expands to 44.3
Base Case $405.82 (+33%)
Market implied 35.1%, PE stable at 40.3
Bear Case $204.22 (-33%)
Severe decline -20.0%, PE contracts to 34.2
These are projections based on PE multiples and EPS growth scenarios, not predictions. Actual results may vary significantly.
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Last updated: May 21, 2026 8:30 PM ET
Data refreshes hourly during market hours. Next update: 9:30 PM
🔥 Top Stocks Breaking Out Now
Ticker Score Recommendation Change %
Insider Activity (6 Months)
0
Buys
10
Sells
Net
INSIDERS SELLING
Recent Transactions
Suma Krishnan SELL 25000 shares 2026-03-04
Kathryn Romano SELL 750 shares 2026-03-02
Daniel Janney SELL 11803 shares 2026-02-27

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Advanced KRYS Option Strategies

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