SYRE Stock Analysis: Buy, Sell, or Hold?

SYRE - Spyre Therapeutics, Inc. Common Stock

PHARMACEUTICAL PREPARATIONS
$81.21
0.42 (0.52%) ▲
5d: +12.79%
30d: +7.35%
90d: +84.28%
HOLD
MODERATE Confidence
Analysis Updated: Jun 12, 2026 12:00 AM ET
Earnings: Aug 04, 2026

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Interactive Price Chart (1 Month)

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💡
Bottom Line:
📊 HOLD: SYRE shows balanced signals. Fine to hold or accumulate slowly. Monitor for clearer direction.
See Forward Earnings Fair Value & Price Prediction →

In-depth Analysis How we analyze

Valuation Analysis: SYRE is currently trading at $81.21, which is considered extended relative to its 30-day fair value range of $70.67 to $76.19.

Technical Outlook: Technically, SYRE is in a strong uptrend. Immediate support is located at $68.50, while resistance sits at $84.43.

Market Sentiment: SYRE has a strong technical setup (75/100), with favorable trendlines, momentum, and price action for short-term traders. Wall Street analysts see significant upside, with an average price target of $96.07 (+18.9%). The stock is fairly positioned - fine to hold existing positions or accumulate slowly on dips, but not an urgent buy.

Quick Decision Summary

Current Position EXTENDED
Historical Trading Range $70.67 - $76.19
Company Quality Score 60/100 (HOLD)
Volume Confirmation HIGH
Confidence Score 55.3%

All Signals

  • BEARISH: Price extended above range (+6.6% above its trading range)
  • BULLISH: Strong technical setup (75/100)
  • BULLISH: High volume confirmation
  • BULLISH: Trading below Wall St target ($96.07)

Trading Range Analysis

30-Day Trading Range $70.67 - $76.19
Current vs Trading Range EXTENDED

Support & Resistance Levels

Support Level $68.50
Resistance Level $84.43
Current Trend Strong Uptrend
Technical data as of Jun 12, 2026

Fundamental Context

Forward P/E (Next Year Est.) -26.65
Wall Street Target $96.07 (+18.9%)
Earnings Growth (YoY) -99.7%
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Last updated: June 15, 2026 10:43 AM ET
Data refreshes hourly during market hours. Next update: 11:43 AM
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Ticker Score Recommendation Change %
Technical Signals Check
Insider Activity (6 Months)
0
Buys
7
Sells
Net
INSIDERS SELLING
Recent Transactions
Cameron Turtle SELL 15000 shares 2026-04-01
Scott L Burrows SELL 7500 shares 2026-04-01
Sheldon Sloan SELL 7958 shares 2026-04-01

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